Human CD8+ T Cells
CD8+ cytotoxic T cells fulfill the dual role of regulating and/or implementing the body’s immune response by eliminating intracellular pathogens such as viruses, bacteria and parasites. Upon recognition of an infected cell, the CD8+ T cell initiates apoptosis through the targeted release of specialized lytic granules within the T cell. CD8+ cytotoxic T cells are isolated from leukopaks by either positive (PS) or negative (NS) selection using immunomagnetic cell separation procedures.
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