How to Order

Because we are shipping live biological products, we need to confirm order information to ensure the biological material do not perish while in transit. A POF is our order confirmation document which ensures that your highly sensitive materials arrive at the correct place and time according to your specifications. Therefore, upon completing the order, a customer must submit the POF.

The form was constructed with four main sections to capture the pertinent information regarding your order.

• Shipping Info: Confirming your shipping address and method is critical to ensure the live biological material is delivered to the right place at the right time. Any discrepancies will default to the address listed on the POF. Please be sure to check the box to confirm the shipping address is correct.
• Billing Info: To ensure a seamless payment process, confirmation of payment method is required prior to shipment of material.
• Product Information: Final review of requested products, receipt date, and confirmation of shipping temperature for each product.
• Sign and Date: Signing-off on the POF indicates that above information is correct and that you agree to Charles River’s Terms and Conditions which states that biological products provided are intended for research use only and not for direct therapeutic or diagnostic use in humans or animals, or for further manufacturing of therapeutic products or devices.

Charles River will begin recruitment and schedule a donor for collection based upon receipt of a signed POF and purchase order/payment.

For GMP-compliant products, a POF is not necessary. Rather, additional agreements between Charles River and the customer may be required to ensure proper product, quality, and regulatory requirements are met.

In an effort to provide a more comprehensive overview of every product we produce, we have redesigned and streamlined our COA.

1. Product Information: New fields include unit volume and vessel type for all products. For fresh material, collection date, start time and end time, and processing date have been added. For cryopreserved material, cryopreservation date is included.
2. Donor Information: COA now includes BMI and available HLA results. Please note that the displayed HLA results are from a donor’s previous screening(s), therefore not all donors may have results. Charles River can provide results of other donor criteria, such as CMV and EBV, for an additional fee.
3. Flow Cytometry Analysis/CBC Information: Improved flow cytometry will be provided for all cryopreserved products and fresh isolated cells. Flow cytometry will be performed on validated instruments using a new qualified, automated method. Software advances allow for consistent gating and display of cell populations across users, instruments, and time. In addition, the new antibody panel comprises recombinant antibodies with mutated Fc regions demonstrating lot-to-lot consistency and elimination of background binding to Fc receptors. All these improvements will allow Charles River to deliver the most robust, consistent enumeration of leukocyte populations.