Additional Donor Information:

When stimulated in vitro with CMV lysate antigen, these CD4+ T cells show a specific proliferative response along with secretion of IFN-gamma, IL-5 and IL-13, but not IL-10. A majority of the T cell population are CD45RO+, CD45RA-, CD62L+, CD127+ and CD28+.

Healthy CMV seropositive female non-smoker. She takes Flonase for seasonal allergies. Genotype at FcgRIIIa is F/F

Additional Donor Information:

Healthy female donor, CMV negative. 5′ 10″ tall, 210 lbs. Her genotype at Fc gamma RIII alpha 158 is F/V.

Additional Donor Information:

These are CD8+ T cells specific for the E7 protein of human papilloma virus. The antigenic peptide sequence is YMLDLQPET representing residues 11-19 of the protein and it is presented by the HLA-A*02:01 allele.

This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.

Additional Donor Information:

These are CD8+ T cells specific for the E7 protein of human papilloma virus. The antigenic peptide sequence is YMLDLQPETT representing residues 11-20 of the protein and it is presented by the HLA-A*02:01 allele. The peptide is available on our Antigens page.

This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.

Additional Donor Information:

T cell population reactive to an HLA-A0201-restricted HPV E7 peptide from position 82-90 (LLMGTLGIV)

This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.

Additional Donor Information:

T cell population reactive to an HLA-A0201-restricted HPV E7 peptide from position 82-90 (LLMGTLGIV)

This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.

Additional Donor Information:

T cell population reactive to an HLA-A0201-restricted HPV E7 peptide from position 82-90 (LLMGTLGIV)

This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.

Additional Donor Information:

These T cells recognize a peptide from glycoprotein D1 [gD1(53-61): SLPITVYYA] of Herpes simplex virus (HSV) presented by HLA-A*0201.

Donor is 5′ 6″ tall and weighs 230 lbs. She has allergies to sulfa drugs and takes Synthroid for thyroid problem. She is F/F at Fc gamma RIII alpha 158.

Additional Donor Information:

These cells are specific for the peptide sequence GILGFVFTL, found in the matrix protein of influenza virus. The peptide is presented (bound by) HLA-A*0201

Healthy CMV seropositive female non-smoker. She takes Flonase for seasonal allergies. Genotype at FcgRIIIa is F/F

Additional Donor Information:

Healthy CMV seropositive female non-smoker. She takes Flonase for seasonal allergies. Genotype at FcgRIIIa is F/F

Additional Donor Information:

MART-1 (Melanoma Antigen Recognized by T cells), also known as Melan-A, is a 118 amino acid long surface protein expressed mainly on melanocytes and most melanoma. This anti MART-1 T cells are CD8+ T cells with specificity to the naturally processed native MART-1 (27-35) 9-mer: AAGIGILTV. These T cells also recognize the analog peptide: ELAGIGILTV, a 10-mer (26-35) with L for A substitution in position 27.

Donor is 5′ 6″ tall and weighs 230 lbs. She has allergies to sulfa drugs and takes Synthroid for thyroid problem. She is F/F at Fc gamma RIII alpha 158.

Additional Donor Information:

MART-1 (Melanoma Antigen Recognized by T cells), also known as Melan-A, is a 118 amino acid long surface protein expressed mainly on melanocytes and most melanoma. This anti MART-1 T cells are CD8+ T cells with specificity to the naturally processed native MART-1 (27-35) 9-mer: AAGIGILTV. These T cells also recognize the analog peptide: ELAGIGILTV, a 10-mer (26-35) with L for A substitution in position 27.

Donor is 5′ 6″ tall and weighs 230 lbs. She has allergies to sulfa drugs and takes Synthroid for thyroid problem. She is F/F at Fc gamma RIII alpha 158.

Additional Donor Information:

An HLA-A*0201-restricted T cell line with the specificity for the KLPDDFTGCV, a peptide that corresponds to the Spike protein (position 424-433) of the novel coronavirus SARS-CoV-2.

Healthy CMV seropositive female non-smoker. She takes Flonase for seasonal allergies. Genotype at FcgRIIIa is F/F

Additional Donor Information:

These CD4+ T cells are specific for a peptide (QYIKANSKFIGITEL) derived from tetanus toxoid bound to HLA-DRB1*01. They also recognize whole tetanus toxoid but only when presented by dendritic cells, not B-LCL.
The T cells proliferate when stimulated with antigen and APC. They also produce IFNg, IL-5, IL-10, and IL-13.

Healthy female donor, CMV negative. 5′ 10″ tall, 210 lbs. Her genotype at Fc gamma RIII alpha 158 is F/V.

Additional Donor Information:

Tyrosinase is a protein involved in melanin synthesis pathway. It is expressed in melanocytes, and both primary and metastatic melanoma cells. This anti-Tyrosinase T cells are CD8+ T cells with specificity to the Tyrosinase (368-376, Asp370) peptide (YMDGTMSQV), restricted by HLA-A*0201.

Donor is 5′ 6″ tall and weighs 230 lbs. She has allergies to sulfa drugs and takes Synthroid for thyroid problem. She is F/F at Fc gamma RIII alpha 158.